Derek Brown is sitting De'Zhaun Stribling in Week 1. That is the clean fantasy answer for managers trying to sort through the 49ers’ passing attack before lineups lock.
The call matters now because Stribling is being treated as the third or fourth option in Week 1, which makes him more dependent on game flow and on the players ahead of him. Brown still sees a path to value later, but not in the opening week of fantasy play.
Brown’s case starts with the player, not the label. Stribling had a solid collegiate career, and his final two seasons showed usable efficiency: 2.15 yards per route run and 2.44 yards per route run, plus 7.3 and 6.7 yards after the catch per reception. He also forced 17 missed tackles across those two seasons, per PFF. Brown said that skill set fits what the 49ers want from their receivers.
That long-view optimism is real. Brown said he likes Stribling’s season-long outlook for 2026 because he worries about the rest of the pass catchers on the team, not named Stribling, staying healthy for the full season. But that is exactly why the Week 1 advice lands where it does: a promising receiver can still be a poor one-week fantasy bet if he is buried behind more established options and is not guaranteed steady volume.
Brown also sees the matchup and role through a more cautious lens because Brock Purdy has a history of producing at a high level and the offense already has other usage points. Over the last three seasons, Purdy has finished as the QB5, QB10 and QB6 in fantasy points per game, and last year he ranked sixth in passing yards per game, ninth in yards per attempt, 12th in highly accurate throw rate and third in fantasy points per dropback among 38 qualifying quarterbacks. He has only once in four NFL seasons finished with a passing touchdown rate below 7.0%, which is one reason the 49ers’ passing pieces can look attractive on paper.
Deebo Samuel’s return on a one-year deal after a one-year dalliance with the Commanders adds another layer to the target picture. Last year, Samuel was the WR29 in fantasy points per game, and among 109 qualifying receivers he finished 18th in target share at 22.4%, ninth in yards after the catch per reception at 6.6, 21st in first-read share at 27.3% and ninth-best in missed tackles forced per reception. He was also 38th in yards per route run, 53rd in first downs per route run at 0.076 and carried a 5.3 aDOT, which ranked 103rd out of 109 qualifying receivers. In a passing game where Samuel remains a central piece, Stribling has to fight for work rather than inherit it.
The matchup does not help much either. The Rams used zone coverage at the seventh-highest rate last year at 76.4%, and over the last three seasons Samuel has posted a 23% target-per-route run rate and 2.06 yards per route run against zone. The Rams were also a solid pass defense, allowing the 11th-fewest yards per attempt, the ninth-lowest passer rating and the 14th-fewest fantasy points per game to quarterbacks, while giving up the 14th-fewest yards per target and fantasy points per opportunity to receivers.
Brown’s recommendation is straightforward: he is sitting Stribling in Week 1. The reason is not that the player lacks a future, but that the first week does not promise enough volume or certainty to trust him. For fantasy managers, that leaves Stribling as a name to remember for later in 2026, not a receiver to force into a lineup now.

