Seattle will visit the Arizona Cardinals at State Farm Stadium on Sunday, September 20, in a Week 2 NFC West game that now carries more uncertainty because of Sam Darnold. The quarterback suffered a hip injury five plays into the season, and his availability for Week 2 is in doubt.
That is why the Cardinals Schedule is drawing attention now. Kickoff is set for 4:25 p.m. ET, and the market has already adjusted around the injury as Seattle goes on the road. Dimers still gives Seattle a 79.1% win probability, yet Arizona +10 is rated as slightly more likely to cover at 51.3%, a split that reflects how far the line has moved without turning the matchup into a true tossup.
Seattle is not walking into this game cold. It beat the New England Patriots in Week 1 and held Drake Maye to 10 points while forcing him into three interceptions, a result that helps explain why the Seahawks remain the road favorite despite the injury concern. The projected score from Dimers is 27-18, with Over 44.5 carrying a 51.1% probability and Under 44.5 at 48.9%.
The friction is simple: Seattle is still treated as the stronger side overall, but the spread tells a different story. Dimers has Arizona with a 20.9% chance to win outright and lists the Cardinals moneyline at +410, which means the home side does not need to win the game for the bet on Arizona +10 to cash. That is the kind of split that usually appears when one team is seen as likely to control the result while the other is considered difficult to separate from the number.
For Seattle and Arizona, that makes Sunday more than an early division date. It is a Week 2 test of how much the injury to Darnold changes the shape of the game before kickoff even arrives. If he is cleared, the Seahawks can lean on the same structure that got them through Week 1. If he is not, the next Cardinals game could look very different from the one the market is already pricing.

