The Cubs and Giants finish their season series this weekend in San Francisco, with Javier Assad scheduled to open Friday night against Landen Roupp at 9:15 p.m. CT. The three games will close out a six-game set between the teams that has been squeezed into 10 days.
Fans looking up Cubs vs Giants now want the matchups and the broadcast details, and they have them for all three days: Friday on Marquee Sports Network, Saturday at 9:05 p.m. CT on Marquee, and Sunday at 2:10 p.m. CT on ABC and the App. Ben Brown is set to face Trevor McDonald on Saturday, and Colin Rea is lined up against Logan Webb for Sunday’s finale, with Jon Sciambi, David Ross and Buster Olney on the call.
Chicago arrives in San Francisco trying to settle things after dropping two of three to the Giants at Wrigley Field last weekend, scoring just seven runs across the series. The Cubs steadied themselves by beating the Rockies 9-3 in their final game before the trip, a win powered by home runs from Seiya Suzuki, Alex Bregman and Carson Kelly, but the weekend now puts the focus back on the matchup that has defined the season set from the start.
The numbers favor Chicago overall. Since the rivalry began in 1883, the Cubs have won 69 more games than they have lost against the Giants, yet that edge softens fast once the games move west. Chicago has lost 147 more road games than it has won against San Francisco, is 163-205 against the Giants in San Francisco and 36-50 at Oracle Park, and it was swept there last season. The Cubs also lost three of four in San Francisco in 2024, won two of three there in 2023 and last swept the Giants in a three-game series in San Francisco in 2013.
That history hangs over a series that does not give either club much room to breathe. The Giants come in after dropping two of three to the Nationals, then rallying from a 9-1 deficit entering the bottom of the eighth to win 11-10 on a walk-off grand slam. Chicago, meanwhile, is still searching for a cleaner road stretch after the loss in Denver earlier this week, and the Cubs are 46 runs shy of their 10,000th run against San Francisco, a milestone that could arrive if this weekend turns into a bigger offensive series than the last one.
For now, the question is less about the rivalry’s long arc than whether the Cubs can do better than they did in their own park and finally take more than one game from a weekend set that now decides the season series. Assad gets the first crack at it Friday night, and by Sunday afternoon the final answer will be on the board at Oracle Park.

